cardiac remodeling after myocardial infarction (MI) is a maladaptive changes associated with progressive heart failure and compromise the long-term clinical outcomes. Most of the patients afflicted by MI still developing adverse outcomes associated with cardiac remodeling. Therefore, it is important to identify biomarkers for early prediction of cardiac remodeling. An in-depth proteomic approaches, including both an array of semi-quantitative and quantitative antibody, is used to identify circulating biomarkers that may be associated with adverse cardiac remodeling.
Furthermore, the statistical correlation analysis was conducted between biomarker candidates and clinical cardiac remodeling the data to demonstrate their clinical utility. A proteomics systematic approach revealed that sclerostin (SOST), differentiation of growth factor-15 (GDF-15), urokinase-type plasminogen activator (uPA) and midkine (MK) increases, while monocytes chemotactic protein – 3 (MCP- 3 ) is a unique decreased in patients who develop cardiac remodeling MI, compared with patients with MI not develop cardiac remodeling and healthy humen.
In addition, the analysis of the correlation between the proteomes of serum and cardiac remodeling parameters of echocardiography showed a positive relationship moderate between left ventricular indexes end-diastolic volume (LVEDVi) and three serum protein , uPA, MK and GDF-15 (P <0 , 05, respectively), and moderate negative correlation between LV ejection fraction (LVEF) and serum is protein (P <0.05, respectively). Importantly, uPA and MK were first identified associated with the development of cardiac remodeling. The research contributes to a better understanding of various cytokines expressed during adverse cardiac remodeling. biomarkers identified could facilitate the early identification of patients at high risk for ischemic heart failure awaiting further confirmation through larger clinical trials.
Prevention of severe intestinal dysfunction Through Barrier Single-Species Probiotic Is Associated With Microbiome-Mediated Activation of Glutamate-Glutamine Biosynthesis Introduction: Intra-abdominal hypertension (IAH), the leading complications in the intensive care unit, significantly disrupt the intestinal microbial composition by reducing the relative abundance of Lactobacillus and increasing the relative abundance of opportunistic infectious bacteria.
Method: In order to evaluate the preventive effect of probiotic-based Lactobacillus at IAH-induced damage intestinal barrier, a-single species of probiotics (L92) and multi-species probiotics (VSL # 3 ) is introduced orally to rats Sprague-Dawley 7 days before inducing IAH. Histology intestine and permeability to macromolecules (isothiocyanate fluoresceine, FITC-dextran, N = 8 for each group), parameter immunomodulatory and response to oxidative [ monocytes chemotactic protein 1 (MCP-1), interleukin-1β (IL-1β), interleukin-4 (IL-4), interleukin-10 (IL-10), malonaldehyde (MDA), glutathione peroxidase (GSH- Px), catalase (CAT) and superoxide dismutase (SOD); N = 4 for each group], and profiling microbiome (N = 4 per group) were analyzed.
Recombinant other Exenatide Protein, Untagged, E.coli-50mg |
|||
| QP11816-50mg | EnQuireBio | 50mg | EUR 2358 |
Recombinant Bovine HTF Protein, Untagged, E.coli-50mg |
|||
| QP12351-50mg | EnQuireBio | 50mg | EUR 155 |
Recombinant E.coli LACTB Protein, Untagged, E.coli-50mg |
|||
| QP12522-50mg | EnQuireBio | 50mg | EUR 3655 |
Recombinant Rat Carboxypeptidase B Protein, Untagged, E.coli-50mg |
|||
| QP10544-50mg | EnQuireBio | 50mg | EUR 517 |
Recombinant Porcine Trypsin Protein, Untagged, Pichia Pastoris-50mg |
|||
| QP10897-50mg | EnQuireBio | 50mg | EUR 962 |
Recombinant Human Trypsin-2 Protein, Untagged, E.coli-50mg |
|||
| QP10899-50mg | EnQuireBio | 50mg | EUR 563 |
Recombinant other HSA Protein, Untagged, Pichia Pastoris-50mg |
|||
| QP12314-50mg | EnQuireBio | 50mg | EUR 201 |
Recombinant other HSA Recombinant Protein, Untagged, Rice-50mg |
|||
| QP12317-50mg | EnQuireBio | 50mg | EUR 363 |
Recombinant Human Collagen-III Protein, Untagged, Pichia Pastoris-50mg |
|||
| QP11479-50mg | EnQuireBio | 50mg | EUR 926 |
Recombinant other HSA Lipid free Protein, Untagged, Rice-50mg |
|||
| QP12316-50mg | EnQuireBio | 50mg | EUR 363 |
(RS)-MCPG |
|||
| HY-100371 | MedChemExpress | 100mg | EUR 946 |
(S)-MCPG |
|||
| HY-100406 | MedChemExpress | 5mg | EUR 133 |
(RS)-MCPG |
|||
| B6265-10 | ApexBio | 10 mg | EUR 248 |
(RS)-MCPG |
|||
| B6265-100 | ApexBio | 100 mg | EUR 1497 |
(RS)-MCPG |
|||
| B6265-25 | ApexBio | 25 mg | EUR 502 |
(RS)-MCPG |
|||
| B6265-5 | ApexBio | 5 mg | EUR 195 |
(RS)-MCPG |
|||
| B6265-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 209 |
(RS)-MCPG |
|||
| B6265-50 | ApexBio | 50 mg | EUR 846 |
(S)-MCPG |
|||
| B6266-10 | ApexBio | 10 mg | EUR 176 |
(S)-MCPG |
|||
| B6266-25 | ApexBio | 25 mg | EUR 350 |
(S)-MCPG |
|||
| B6266-5 | ApexBio | 5 mg | EUR 116 |
DiA: (50mg) |
|||
| 60013 | Biotium | 50MG | EUR 210 |
|
Description: Minimum order quantity: 1 unit of 50MG |
|||
(RS)-MCPG disodium salt |
|||
| B7476-10 | ApexBio | 10 mg | EUR 302 |
(RS)-MCPG disodium salt |
|||
| B7476-50 | ApexBio | 50 mg | EUR 1114 |
Gentamicin, 50mg/ml |
|||
| CA003-001 | GenDepot | 10ml | EUR 91 |
L-NMMA: (50mg) |
|||
| 00224 | Biotium | 25MG | EUR 207 |
|
Description: Minimum order quantity: 1 unit of 25MG |
|||
DiOC14(3), hydroxyethanesulfonate: (50mg) |
|||
| 60012 | Biotium | 50MG | EUR 153 |
|
Description: Minimum order quantity: 1 unit of 50MG |
|||
Biotin-12, SE: (50mg) |
|||
| 90083 | Biotium | 50MG | EUR 193 |
|
Description: Minimum order quantity: 1 unit of 50MG |
|||
Kanamycin solution (50mg/ml) |
|||
| MN800A-1 | SBI | 20 ml | EUR 127 |
DiD (or DiIC18(5)): (50mg) |
|||
| 60014 | Biotium | 50MG | EUR 161 |
|
Description: Minimum order quantity: 1 unit of 50MG |
|||
SAHA (Vorinostat ) |
|||
| P004-50MG | Arbor Assays | 50MG | EUR 119 |
|
Description: CAS: 149647-78-9 |
|||
HPA (Hexyl-4-pentynoic acid ) |
|||
| P008-50MG | Arbor Assays | 50MG | EUR 311 |
|
Description: CAS: 96017-59-3 |
|||
5-Azacytidine |
|||
| P012-50MG | Arbor Assays | 50MG | EUR 86 |
|
Description: CAS: 320-67-2 |
|||
Decitabine |
|||
| P015-50MG | Arbor Assays | 50MG | EUR 539 |
|
Description: CAS: 2353-33-5 |
|||
BRL-50481 |
|||
| P020-50MG | Arbor Assays | 50 mg | EUR 441 |
|
Description: CAS: 433695-36-4 |
|||
Xanthohumol |
|||
| P021-50MG | Arbor Assays | 50MG | EUR 1001 |
|
Description: CAS: 6754-58-1 |
|||
Quercetin dihydrate EvoPure® |
|||
| Q002-50MG | TOKU-E | 50 mg | EUR 138 |
Salinomycin sodium |
|||
| S002-50MG | TOKU-E | 50 mg | EUR 102 |
Sulbactam |
|||
| S010-50MG | TOKU-E | 50 mg | EUR 272 |
Synercid |
|||
| S018-50MG | TOKU-E | 50mg | EUR 730 |
Sancycline hydrochloride |
|||
| S076-50MG | TOKU-E | 50 mg | EUR 440 |
α-Mangostin |
|||
| M076-50MG | TOKU-E | 50 mg | EUR 523 |
γ-Mangostin |
|||
| M077-50MG | TOKU-E | 50 mg | EUR 967 |
Miltefosine |
|||
| M085-50MG | TOKU-E | 50 mg | EUR 95 |
Mosapride Citrate |
|||
| M099-50MG | TOKU-E | 50mg | EUR 371 |
Natamycin |
|||
| N002-50MG | TOKU-E | 50 mg | EUR 70 |
Nigericin sodium |
|||
| N015-50MG | TOKU-E | 50 mg | EUR 563 |
Naftifine hydrochloride |
|||
| N047-50MG | TOKU-E | 50 mg | EUR 138 |
Neochlorogenic acid |
|||
| N050-50MG | TOKU-E | 50 mg | EUR 617 |
Nitazoxanide |
|||
| N052-50MG | TOKU-E | 50 mg | EUR 213 |
Neratinib |
|||
| N067-50MG | TOKU-E | 50mg | EUR 110 |
Lamivudine |
|||
| L019-50MG | TOKU-E | 50 mg | EUR 282 |
Lasalocid Sodium |
|||
| L026-50MG | TOKU-E | 50 mg | EUR 119 |
Lenvatinib |
|||
| L051-50MG | TOKU-E | 50mg | EUR 238 |
Meropenem USP |
|||
| M002-50MG | TOKU-E | 50 mg | EUR 171 |
Mitoxantrone hydrochloride |
|||
| M010-50MG | TOKU-E | 50 mg | EUR 129 |
Mycophenolic Acid |
|||
| M012-50MG | TOKU-E | 50 mg | EUR 73 |
Mupirocin |
|||
| M022-50MG | TOKU-E | 50 mg | EUR 276 |
Pristinamycin |
|||
| P018-50MG | TOKU-E | 50mg | EUR 889 |
Pneumocandin B0 |
|||
| P092-50MG | TOKU-E | 50 mg | EUR 229 |
Permethrin |
|||
| P106-50MG | TOKU-E | 50 mg | EUR 73 |
Oritavancin Diphosphate |
|||
| O032-50MG | TOKU-E | 50mg | EUR 481 |
Flucloxacillin sodium |
|||
| F009-50MG | TOKU-E | 50 mg | EUR 312 |
Faropenem sodium |
|||
| F016-50MG | TOKU-E | 50mg | EUR 242 |
Fidaxomicin |
|||
| F025-50MG | TOKU-E | 50 mg | EUR 105 |
Ganciclovir |
|||
| G002-50MG | TOKU-E | 50 mg | EUR 190 |
Rucaparib camsylate |
|||
| R044-50MG | TOKU-E | 50mg | EUR 273 |
Rocuronium Bromide |
|||
| R045-50MG | TOKU-E | 50mg | EUR 102 |
Indomethacin morpholinylamide |
|||
| I039-50MG | TOKU-E | 50 mg | EUR 227 |
Ertapenem sodium EvoPure® |
|||
| E008-50MG | TOKU-E | 50 mg | EUR 277 |
Daunorubicin hydrochloride |
|||
| D001-50MG | TOKU-E | 50 mg | EUR 400 |
Daptomycin |
|||
| D024-50MG | TOKU-E | 50 mg | EUR 178 |
Dihydrozeatin (DHZ) |
|||
| D071-50MG | TOKU-E | 50 mg | EUR 186 |
Dihydrotanshinone I |
|||
| D078-50MG | TOKU-E | 50 mg | EUR 394 |
Dalbavancin Hydrochloride |
|||
| D092-50MG | TOKU-E | 50mg | EUR 380 |
Embelin |
|||
| E063-50MG | TOKU-E | 50 mg | EUR 252 |
Emodin |
|||
| E064-50MG | TOKU-E | 50 mg | EUR 112 |
Epigallocatechin gallate |
|||
| E065-50MG | TOKU-E | 50 mg | EUR 84 |
Enniatin |
|||
| E039-50MG | TOKU-E | 50 mg | EUR 1082 |
Everolimus |
|||
| E058-50MG | TOKU-E | 50 mg | EUR 236 |
Telithromycin |
|||
| T015-50MG | TOKU-E | 50 mg | EUR 291 |
Tedizolid |
|||
| T117-50MG | TOKU-E | 50mg | EUR 481 |
Tedizolid Phosphate |
|||
| T118-50MG | TOKU-E | 50mg | EUR 180 |
Tipiracil Hydrochloride |
|||
| T121-50MG | TOKU-E | 50mg | EUR 340 |
Tolvaptan |
|||
| T125-50MG | TOKU-E | 50mg | EUR 429 |
Tenofovir Alafenamide |
|||
| T128-50MG | TOKU-E | 50mg | EUR 144 |
Phenyl b-D-thioglucopyranoside |
|||
| GC0722-50MG | Glentham Life Sciences | 50 mg | EUR 70 |
b-D-Allopyranose |
|||
| GC0862-50MG | Glentham Life Sciences | 50 mg | EUR 61 |
5-Bromo-4-chloro-3-indolyl b-D-xylopyranoside |
|||
| GC1526-50MG | Glentham Life Sciences | 50 mg | EUR 94 |
Methyl N-acetyl-alpha-D-glucosaminide |
|||
| GC2856-50MG | Glentham Life Sciences | 50 mg | EUR 142 |
Maltohexaose |
|||
| GC2935-50MG | Glentham Life Sciences | 50 mg | EUR 86 |
5-Bromo-4-chloro-3-indolyl b-D-galactopyranoside |
|||
| GC3237-50MG | Glentham Life Sciences | 50 mg | EUR 54 |
XTT sodium salt |
|||
| GC5281-50MG | Glentham Life Sciences | 50 mg | EUR 142 |
Quercetin 3-b-D-glucoside |
|||
| GC9169-50MG | Glentham Life Sciences | 50 mg | EUR 114 |
Spiperone hydrochloride |
|||
| GE2928-50MG | Glentham Life Sciences | 50 mg | EUR 154 |
AEBSF hydrochloride |
|||
| GE4678-50MG | Glentham Life Sciences | 50 mg | EUR 114 |
5-Methyl-2'-deoxycytidine |
|||
| GE5158-50MG | Glentham Life Sciences | 50 mg | EUR 75 |
Asiaticoside |
|||
| GC7829-50MG | Glentham Life Sciences | 50 mg | EUR 344 |
Stevioside |
|||
| GC8309-50MG | Glentham Life Sciences | 50 mg | EUR 367 |
Trifluridine |
|||
| GE1913-50MG | Glentham Life Sciences | 50 mg | EUR 102 |
Actinomycin D |
|||
| GA0481-50MG | Glentham Life Sciences | 50 mg | EUR 174 |
Ascomycin |
|||
| GA1406-50MG | Glentham Life Sciences | 50 mg | EUR 285 |
Mupirocin |
|||
| GA2184-50MG | Glentham Life Sciences | 50 mg | EUR 82 |
Flumethasone |
|||
| GA2414-50MG | Glentham Life Sciences | 50 mg | EUR 70 |
Telithromycin |
|||
| GA2425-50MG | Glentham Life Sciences | 50 mg | EUR 150 |
Linezolid |
|||
| GA2609-50MG | Glentham Life Sciences | 50 mg | EUR 126 |
Brefeldin A |
|||
| GA2848-50MG | Glentham Life Sciences | 50 mg | EUR 389 |
Doxorubicin hydrochloride |
|||
| GA4969-50MG | Glentham Life Sciences | 50 mg | EUR 126 |
Torezolid |
|||
| GA5035-50MG | Glentham Life Sciences | 50 mg | EUR 90 |
Pimaricin |
|||
| GA5100-50MG | Glentham Life Sciences | 50 mg | EUR 50 |
Ribavirin |
|||
| GA5462-50MG | Glentham Life Sciences | 50 mg | EUR 62 |
Phleomycin |
|||
| GA6020-50MG | Glentham Life Sciences | 50 mg | EUR 269 |
Biapenem |
|||
| GA6808-50MG | Glentham Life Sciences | 50 mg | EUR 78 |
Vinblastine sulfate |
|||
| GA7194-50MG | Glentham Life Sciences | 50 mg | EUR 389 |
Rapamycin |
|||
| GA7417-50MG | Glentham Life Sciences | 50 mg | EUR 150 |
Ceftibuten hydrate |
|||
| GA7818-50MG | Glentham Life Sciences | 50 mg | EUR 120 |
Mitomycin C |
|||
| GA9147-50MG | Glentham Life Sciences | 50 mg | EUR 269 |
Moxifloxacin hydrochloride |
|||
| GA9781-50MG | Glentham Life Sciences | 50 mg | EUR 54 |
Ribonuclease A, DNase free |
|||
| GE9871-50MG | Glentham Life Sciences | 50 mg | EUR 107 |
PD 98,059 |
|||
| GK2140-50MG | Glentham Life Sciences | 50 mg | EUR 378 |
Aminopterin dihydrate |
|||
| GK2974-50MG | Glentham Life Sciences | 50 mg | EUR 107 |
Pravastatin sodium salt |
|||
| GK3699-50MG | Glentham Life Sciences | 50 mg | EUR 110 |
alpha-Mangostin |
|||
| GK4316-50MG | Glentham Life Sciences | 50 mg | EUR 269 |
3-Morpholinosydnonimine hydrochloride |
|||
| GK4946-50MG | Glentham Life Sciences | 50 mg | EUR 200 |
H-8 dihydrochloride |
|||
| GK6037-50MG | Glentham Life Sciences | 50 mg | EUR 252 |
Ro 61-8048 |
|||
| GK6422-50MG | Glentham Life Sciences | 50 mg | EUR 548 |
Cisapride monohydrate |
|||
| GL0434-50MG | Glentham Life Sciences | 50 mg | EUR 229 |
AdipoRon hydrochloride |
|||
| GL0874-50MG | Glentham Life Sciences | 50 mg | EUR 459 |
Mephenytoin |
|||
| GL1129-50MG | Glentham Life Sciences | 50 mg | EUR 429 |
1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one |
|||
| GL1507-50MG | Glentham Life Sciences | 50 mg | EUR 321 |
MTSSL |
|||
| GL1695-50MG | Glentham Life Sciences | 50 mg | EUR 436 |
Tocainide hydrochloride |
|||
| GL2205-50MG | Glentham Life Sciences | 50 mg | EUR 429 |
Thonzonium bromide |
|||
| GL2255-50MG | Glentham Life Sciences | 50 mg | EUR 166 |
WY-14643 |
|||
| GL2940-50MG | Glentham Life Sciences | 50 mg | EUR 154 |
Compound 112254 |
|||
| GL3740-50MG | Glentham Life Sciences | 50 mg | EUR 459 |
Cyclic Pifithrin-alpha hydrobromide |
|||
| GL3913-50MG | Glentham Life Sciences | 50 mg | EUR 528 |
Shikonin |
|||
| GL5964-50MG | Glentham Life Sciences | 50 mg | EUR 269 |
TOFA |
|||
| GL6289-50MG | Glentham Life Sciences | 50 mg | EUR 198 |
4-Aminophenylphosphate sodium salt |
|||
| GL6836-50MG | Glentham Life Sciences | 50 mg | EUR 252 |
N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine |
|||
| GK2289-50MG | Glentham Life Sciences | 50 mg | EUR 77 |
SC-560 |
|||
| GK2799-50MG | Glentham Life Sciences | 50 mg | EUR 349 |
Piperlongumine |
|||
| GK8547-50MG | Glentham Life Sciences | 50 mg | EUR 223 |
Bay 11-7082 |
|||
| GK8638-50MG | Glentham Life Sciences | 50 mg | EUR 413 |
PK 11195 |
|||
| GL4857-50MG | Glentham Life Sciences | 50 mg | EUR 321 |
MnTBAP chloride |
|||
| GL5377-50MG | Glentham Life Sciences | 50 mg | EUR 154 |
AdipoRon |
|||
| GL6438-50MG | Glentham Life Sciences | 50 mg | EUR 390 |
Epicoprostanol |
|||
| GL6737-50MG | Glentham Life Sciences | 50 mg | EUR 137 |
Zerumbone |
|||
| GL7258-50MG | Glentham Life Sciences | 50 mg | EUR 298 |
GYY 4137 |
|||
| GL7524-50MG | Glentham Life Sciences | 50 mg | EUR 321 |
L-Alanyl-L-1-aminoethylphosphonic acid |
|||
| GL8388-50MG | Glentham Life Sciences | 50 mg | EUR 158 |
Corosolic acid |
|||
| GL8496-50MG | Glentham Life Sciences | 50 mg | EUR 668 |
MnTMPyP pentachloride |
|||
| GL8780-50MG | Glentham Life Sciences | 50 mg | EUR 154 |
Compound 112254 hydrochloride |
|||
| GL8859-50MG | Glentham Life Sciences | 50 mg | EUR 459 |
Ketanserin (+)-tartrate salt |
|||
| GL9943-50MG | Glentham Life Sciences | 50 mg | EUR 172 |
Bay 60-7550 |
|||
| GN2518-50MG | Glentham Life Sciences | 50 mg | EUR 2582 |
5-(E)-(2-Bromovinyl)-2'-deoxyuridine |
|||
| GN2626-50MG | Glentham Life Sciences | 50 mg | EUR 150 |
3'-O-Methylguanosine |
|||
| GN3227-50MG | Glentham Life Sciences | 50 mg | EUR 190 |
N1-Methyladenosine |
|||
| GN7727-50MG | Glentham Life Sciences | 50 mg | EUR 269 |
Pseudouridine |
|||
| GN9104-50MG | Glentham Life Sciences | 50 mg | EUR 128 |
Rizatriptan benzoate |
|||
| GP0042-50MG | Glentham Life Sciences | 50 mg | EUR 150 |
Suramin sodium salt |
|||
| GP0138-50MG | Glentham Life Sciences | 50 mg | EUR 110 |
Rofecoxib |
|||
| GP0159-50MG | Glentham Life Sciences | 50 mg | EUR 86 |
Epigallocatechin gallate |
|||
| GP0260-50MG | Glentham Life Sciences | 50 mg | EUR 72 |
Betaxolol hydrochloride |
|||
| GP0555-50MG | Glentham Life Sciences | 50 mg | EUR 110 |
Tonabersat |
|||
| GP0580-50MG | Glentham Life Sciences | 50 mg | EUR 628 |
Salmeterol xinafoate |
|||
| GP0706-50MG | Glentham Life Sciences | 50 mg | EUR 94 |
Boceprevir |
|||
| GP0844-50MG | Glentham Life Sciences | 50 mg | EUR 778 |
Perindopril erbumine |
|||
| GP1522-50MG | Glentham Life Sciences | 50 mg | EUR 92 |
Valaciclovir hydrochloride |
|||
| GP1612-50MG | Glentham Life Sciences | 50 mg | EUR 46 |
Forskolin |
|||
| GP2059-50MG | Glentham Life Sciences | 50 mg | EUR 309 |
Gatifloxacin hydrate |
|||
| GP2111-50MG | Glentham Life Sciences | 50 mg | EUR 90 |
Sunitinib malate |
|||
| GP2160-50MG | Glentham Life Sciences | 50 mg | EUR 102 |
Methysergide maleate salt |
|||
| GP2886-50MG | Glentham Life Sciences | 50 mg | EUR 668 |
Bosentan hydrate |
|||
| GP5893-50MG | Glentham Life Sciences | 50 mg | EUR 130 |
Carmofure |
|||
| GP5925-50MG | Glentham Life Sciences | 50 mg | EUR 154 |
Zafirlukast |
|||
| GP6218-50MG | Glentham Life Sciences | 50 mg | EUR 110 |
Tolazamide |
|||
| GP6227-50MG | Glentham Life Sciences | 50 mg | EUR 237 |
Lopinavir |
|||
| GP6351-50MG | Glentham Life Sciences | 50 mg | EUR 70 |
Acadesine |
|||
| GP6637-50MG | Glentham Life Sciences | 50 mg | EUR 154 |
Indinavir sulphate hydrate |
|||
| GP6821-50MG | Glentham Life Sciences | 50 mg | EUR 126 |
Acepromazine maleate |
|||
| GP6873-50MG | Glentham Life Sciences | 50 mg | EUR 110 |
Curcumin, pure, 98% |
|||
| GP7022-50MG | Glentham Life Sciences | 50 mg | EUR 160 |
Saquinavir mesylate |
|||
| GP7183-50MG | Glentham Life Sciences | 50 mg | EUR 150 |
Levosimendan |
|||
| GP7196-50MG | Glentham Life Sciences | 50 mg | EUR 110 |
Nelfinavir mesylate |
|||
| GP7332-50MG | Glentham Life Sciences | 50 mg | EUR 349 |
Celastrol |
|||
| GP7348-50MG | Glentham Life Sciences | 50 mg | EUR 620 |
Apixaban |
|||
| GP7497-50MG | Glentham Life Sciences | 50 mg | EUR 126 |
Results: 7 days pretreatments of L92 significantly reduced IAH-induced increase in intestinal permeability to FITC-dextran and histological damage (P <0.0001), accompanied by the suppression of inflammation and oxidative activation. Increased MCP-1 and IL-1β was significantly inhibited (P <0.05); anti-inflammatory cytokine, IL-4 and IL-10 were maintained at a high level; and oppression CAT (P <0.05) significantly reversed when pretreated with L92.
